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S. Give

At a Glance

Antigenic Formula 3,{10}{15}{15,34}:l,v:1,7
Serogroup O:3,10 (E1)
NCBI Pathogen Detection View isolates

Background Information

Salmonella enterica subsp. enterica serovar Give (antigenic formula: 3,{10}{15}{15,34}:l,v:1,7) is a serovar of the O:3,10 (E1) serogroup. This serovar has been reported to cause brain abscess and bacteremia in a 3-year old female child. Serovar Give was associated with a cattle outbreak, but further details regarding the incident are unavailable.

Genetic Characteristics

Serovar Give has been found to be polyphyletic with two lineages identified. In a Venezuela study, the blaTEM-1 and blaSHV-12 genes were identified in S. Give SG9611, while blaTEM-1 and blaCTX-M-2 were found in the other three strains: S. Give SG9811, S. Heidelberg SH7511, and SH7911. Notably, the qnrB19 gene was detected in all four strains, irrespective of their origin or serovars. In an outbreak study, all human isolates analyzed in clusters 1 and 2 through MLST exhibited resistance to monoglucoside. In pig farms in Ibadan, Nigeria, the majority of the multidrug-resistant isolates were S. Give, comprising 24 isolates (47.1%), which exhibited co-resistance to nalidixic acid, chloramphenicol, and tetracycline.

Animal Reservoir

Unknown but serovar Give has previously been isolated in livestock such as cattle, pigs, and exotic animals such as camels.

Geographical Distribution

Serovar Give has been reported worldwide such as the UK and the US.

Human/Animal Outbreaks

Year Location Associated source Number of cases
2022 Greece Roasted pork 10
2016 Malta Local food manufacturer1 36
2008 France Formula milk 8
2004 Germany Raw pork mince 115

1 Salmonella Give were found in packaged bean dips, ham, and pork.

Border Rejections

Year Exporting country Importing country Associated source Product category
2023 Belarus Lithuania Rapeseed expeller Feed materials
2021 Brazil Germany Black pepper1 Herbs and spices
2021 India Netherlands Turmeric powder 2% curcumine2 Herbs and spices

1 Salmonella Infantis and Give were both found.

2 Informing consignor and Distribution restricted to notifying country

Recalls

Year Location Recalled food Type
2025 Czech Republic Chilled duck with giblets from Hungary1 Poultry meat and poultry meat products

1 Product (presumably) was no longer on the market.

References

  1. https://pubmed.ncbi.nlm.nih.gov/38176586/
  2. https://pubmed.ncbi.nlm.nih.gov/5464488/
  3. https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1547190/full
  4. https://pubmed.ncbi.nlm.nih.gov/24187555/
  5. https://link.springer.com/article/10.1007/s12223-013-0270-6
  6. https://www.rrh.org.au/journal/article/8391
  7. https://www.cambridge.org/core/journals/epidemiology-and-infection/article/national-outbreak-of-salmonella-give-linked-to-a-local-food-manufacturer-in-malta-october-2016/F086A81E491E0272ABE4869A7C62DD60
  8. https://www.eurosurveillance.org/content/10.2807/ese.13.39.18994-en
  9. https://pubmed.ncbi.nlm.nih.gov/16088767/
  10. https://webgate.ec.europa.eu/rasff-window/screen/notification/609318
  11. https://webgate.ec.europa.eu/rasff-window/screen/notification/504801
  12. https://webgate.ec.europa.eu/rasff-window/screen/notification/471596
  13. https://webgate.ec.europa.eu/rasff-window/screen/notification/746029