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S. Hartford

At a Glance

Antigenic Formula 6,7:y:e,n,x
Serogroup O:7 (C1)
NCBI Pathogen Detection View isolates

Background Information

Salmonella enterica subsp. enterica serovar Hartford (antigenic formula 6,7:​y:e,n,x) is a serovar of the O:7 (C1) serogroup. Serovar Hartford was previously recovered from non-outbreak cattle herds. Serovar Hartford was found as highly persistent in all low-aw food ingredients.

Genetic Characteristics

Serovar Hartford has been found to be polyphyletic with two lineages identified and one stand-alone singleton that does not cluster with any other Salmonella Hartford isolates. In a US study, serovar Hartford isolates were found to be pansusceptible to all antimicrobials tested using the Kirby-Bauer method. Additionally, all six Hartford isolates recovered from mesenteric lymph nodes on one of farms were indistinguishable based on pulsed-field gel electrophoresis analysis.

Animal Reservoir

Salmonella Hartford was found inchicken, calves, horses, dogs, and wild animals such as wild black bears.

Geographical Distribution

Serovar Hartford has been found in the US, Canada, Australia, the UK, Hungary, and China.

Human/Animal Outbreaks

Year Location Associated Source Number of Cases
2023 US: multistate Not identified 54
2014 US: multistate Organic sprouted chia powder1 31
2010 US: multistate Not identified 75
1995 US: FL Unpasteurized orange juice2 62

1 Salmonella Newport (20 cases), Salmonella Hartford (7 cases), or Salmonella Oranienburg (4 cases)

2 Salmonella Gaminara was also involved in this outbreak.

Border rejections: There have been no recent border rejections linked to this serovar.

Recalls

There have been no recent recalls linked to this serovar.

References

  1. https://www.liebertpub.com/doi/10.1089/fpd.2017.2303?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
  2. https://www.sciencedirect.com/science/article/pii/S0362028X22106150
  3. https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1547190/full
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC4652083/
  5. https://www.mdpi.com/2076-2607/11/2/403
  6. https://www.jstor.org/stable/24320783
  7. https://www.fda.gov/food/outbreaks-foodborne-illness/investigations-foodborne-illness-outbreaks
  8. https://archive.cdc.gov/www_cdc_gov/salmonella/newport-05-14/index.html
  9. https://archive.cdc.gov/#/details?url=https://www.cdc.gov/salmonella/2010/restaurant-chain-a-8-4-10.html
  10. https://jamanetwork.com/journals/jama/fullarticle/188128